STUDIES ON THE SHOPE RABBIT PAPILLOMA VIRUS
نویسندگان
چکیده
منابع مشابه
Studies on the Shope Rabbit Papilloma Virus
A method has been devised to determine the location of infective Shope virus in the papillomas of cottontail rabbits. Frozen sections of the growths were burned selectively with a microcautery to destroy either the keratinized or proliferating layer and the sections were then applied directly to the sensitized epidermis of domestic rabbits. No papillomas appeared when the keratohyaline and kera...
متن کاملStudies of the Mechanism of Action of the Shope Rabbit Papilloma Virus
These studies make plain that the Shope papilloma virus induces the production of an arginase in rabbit squamous epithelium, and provide evidence that the information for the synthesis of the enzyme is derived from the virus rather than the rabbit. This form of induction is therefore different from that brought about by chemicals such as galactosides (36). Striking differences were shown betwee...
متن کاملThe Roentgen Radiation of Papilloma Virus (shope)
Virus-induced papillomas (Shope) on domestic rabbits are susceptible to Roentgen rays. The dosage which uniformly brings about their complete and permanent disappearance has been found to be 3600 r (200 kilovolts), whether this dose be administered at one time or fractionally. 60 per cent of the tumors are cured when irradiated with 3000 r.
متن کاملThe Masking Effect of Extravasated Antibody on the Rabbit Papilloma Virus (shope)
The foregoing experiments have shown that the causative virus is usually "masked" in the large, disorderly, fissured and inflamed papillomas of cottontails when antiviral antibody is present in quantity in their blood, though virus can be recovered as a rule from the smaller, discrete, well ordered papillomas of these rabbits, almost irrespective of the amount of antibody in the blood of the in...
متن کاملThe Superinfection of the Rabbit Papilloma (shope) by Extraneous Viruses
1. The potentialities that viruses have for the superinfection of virus tumors have not been recognized nor has the fact that a single cell can harbor more than one virus. 2. Rabbit papillomas, induced by the papilloma virus (Shope), were superinfected by B virus, myxoma virus, vaccinia virus, and probably, virus III. Similar attempts at superinfection by herpes virus were without success. The ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1959
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.109.4.423